Dr. Alessandro Canelli, Mayor

Prof. Gian Carlo Avanzi, Rector

Dr. Gianfranco Zulian, Hospital Chief Executive

Dr. Matteo Marnati, Regional Minister

Prof. Gianluca Gaidano, Head of School of Medicine

Prof. Lia Rimondini, Head of DISS

Prof. Gianluca Aimaretti, Head of DIMET

Prof. Ciro Isidoro, Head of the Conference

3.15 - 3.45 PM     

Title: The biology of minimal residual disease of CLL (KL)

Davide Rossi

3.45 - 4.15 PM     

Title: Counteracting gemcitabine+nab-paclitaxel induced dysbiosis in KRAS wild type and KRASG12D mutated pancreatic cancer in vivo model (KL)

Valerio Pazienza

4.15 - 4.40 PM     

Title: Is cancer reversible? Experimental evidence on the reversibility of the malignant tumor phenotype (IL)

Andrea Pensotti

4.40 - 4.50 PM

Title: Molecular clustering on ctDNA improves the prognostic stratification of DLBCL patients compared to ctDNA levels (SC)

Mohammad Almasri

4.50 - 5.00 PM     

Title: Assessment of lipidomic profile in Endocrine Receptor positive (ER+) MBC patients treated with CD4/6 inhibitors and endocrine therapy (SC)

Rahma Ben Ayed

5.00 - 5.10 PM    

Title: Heme catabolism by tumor-associated macrophages controls metastasis formation (SC)

Francesca Maria Consonni

5.10 - 5.15 PM     

Title: Evaluation of Extracellular Vescicles (EVs) as potetial predictior of response to immunotherapy (IO) in triple negative early and advanced breast cancer (BC): preliminary evidence from the IRIS (FC)

Rami Alsati

Social event

Social event

8.35 - 9.00 AM   

Title: KRAS-regulated glutamine metabolism requires UCP2-mediated aspartate transport to support pancreatic cancer growth (IL)

Giuseppe Fiermonte

9.00 - 9.25 AM     

Title: From diet to postbiotics: tuning the gut microbiota to hinder multiple myeloma (IL)

 Matteo Bellone

9.25 - 9.50 AM      

Title: Reactive Oxygen Species and Nitric Oxide are involved in cell migration/invasion in murine melanoma cells  (IL)

Arnold Stern

9.50 - 10.05 AM     

Title: How a PI3K interactor drives PDAC chemoresistance and metastasis while paving the way for PI3K-targeted therapy (OC)

Andrea Costamagna

10.05 - 10.15 AM    

Title: The microbiota metabolite butyrate inhibits IL-6-induced colorectal cancer cell migration by sequestering β-catenin into the autophagosome  (SC)

Letizia Vallino

10.15 - 10.25 AM    

Title: The cellular deacetylase SIRT1 contributes to HPV-driven p53 inhibition and it is an actionable therapeutic target (SC)

Federica Calati

10.25 - 10.35 AM     

Title: The role of Rab40 families in regulating GTPases during breast cancer cell migration (SC)

Revathi Sampath

10.35 - 10.45 AM    

Title: Butyrate induces autophagy degradation of β–catenin inhibiting colorectal cancer cell proliferation regardless APC and β–catenin mutational status  (SC)

Beatrice Garavaglia

10.45 - 10.55 AM    

Title: Characterization of novel beclin-1 splicing isoforms and their role in autophagy in cancer cells  (SC)

Chinmay Maheshwari

10.55 -11.00 PM      

Title: Role of diacylglycerol kinases in acute myeloid leukemia (FC)

Elisa Gorla

11.30 AM - 11.45 AM    

Title: Effect of neoadjuvant chemotherapy on peripheral exhausted and senescent of T cells in breast cancer patients (OC)

Veronica Martini

11.45 AM - 12.15 PM       

Title: Microtubule-regulating proteins as predictive biomarkers of chemoresistance in breast and ovarian cancer (KL)

Clara Nahmias

12.15 - 12.40 PM        

Title: Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer (IL)

Guillermo Barreto

12.40 - 1.05 PM          

Title: Autophagy and cancer  (IL)

Devrim Gozuacik

1.05 - 1.15 PM          

Title: Factor VIII: A potential player in cancer pathophysiology (SC)

Gillian Walker

1.15 - 1.25 PM          

Title: Resveratrol counteracts IL-6-induced ovarian cancer cell proliferation by promoting autophagy-mediated cancer cell dormancy: role of miR-1305, a novel oncomiRNA  (SC)

Andrea Esposito

1.25 - 1.30 PM          

Title: Clonal hematopoiesis in chronic lymphocytic leukemia (FC)

Chiara Cosentino

2.30 - 2.45 PM    

Title: XPO1 mutations identify early stage CLL characterized by shorter time to first treatment and enhanced BCR signaling (OC)

Riccardo Moia

2.45 - 3.00 PM    

Title: Cancer-associated fibroblast phenoconverison relies on glucose-dependent inhibition of autophagy (OC)

Alessandra Ferraresi

3.00 - 3.25 PM     

Title: A novel approach to target BMP-resistance in cancer cachexia skeletal muscle atrophy (IL)

Paolo Ettore Porporato

3.25 - 3.50 PM    

Title: NAD+ metabolism in cancer cachexia (IL)

Fabio Penna

3.50 - 4.05 PM   

Title:  Targeting the estrogen receptor signaling pathway as a new therapeutic strategy against endocrine therapy-resistant breast cancer  (OC)

Annamaria Salvati

4.05 - 4.20 PM     

Title: Virtual microdissection of non-small cell lung cancer identifies transcriptome-based tumor-specific and immune-specific molecular subtypes (OC)

Sushant Parab

4.20 - 4.30 PM      

Title: High BECN1 expression negatively correlates with BCL2 expression and predicts better prognosis in diffuse large B-cell lymphoma: role of autophagy (SC)

Amreen Salwa

4.30 - 4.45 PM      

Title: An exemplary model of tumor reversion triggered  by either inositol or oocyte's miRNAs (OC)

Noemi Monti 

4.45 - 4.55 PM      

Title: The RIG-1 agonist M8 triggers cell death and natural killer cell activation in human papillomavirus-associated cancer and potentiates cisplatin cytotoxicity (SC)

Carlo Girone

4.55 - 5.05 PM      

Title: Vitamin D binding protein contributes to cancer-associated muscle wasting  (SC)

Tommaso Raiteri

5.05 - 5.15 PM      

Title: Vitamin D binding protein has a pro-athropic effect on C2C12 myotubes (SC)

Andrea Scircoli

5.15 - 5.25 PM      

Title: Circulating tumor cells as a potential biomarker for predicting recurrence of hepatocellular carcinoma (SC)

Daria Apostolo

5.25 - 5.30 PM      

Title: Analysis of the metabolimic profile in early breast cancer patients treated with neoadjuvant chemotherapy (FC)

Simone Gobbato

5.30 - 5.35 PM      

Title: OPN/ICOSL interaction promotes metastasis formation in melanoma development  (FC)

Beatrice Vilardo

5.35 - 5.40 PM      

Title:  Distinct signatures of mucosa-associted microbiota and metabolome in low-grade vs hig-grade dysplastic colon polyps (FC)

Gloria Sala

5.40 - 6.10 PM      

Title: Ethnic diversity in ovarian cancer metabolome: a promising avenue for targeted therapy (Keynote Closing Lecture)

Danny N. Dhanasekaran

Prof. Gianluca Gaidano

Prof. Danny N. Dhanasekaran

Prof. Ciro Isidoro

Social event